PROJECT SUMMARY The goals of the Robert and Arlene Kogod Center on Aging Training Program are to provide multidisciplinary research opportunities for postdoctoral fellows at Mayo Clinic and to train them to be future leaders of biomedical research in aging and age-related diseases. This is of critical importance in order to increase the quality of life for the elderly as well as to reduce the societal and economic burden of chronic diseases and frailty of age. Thus, this program aims to provide outstanding research and educational opportunities within the setting of a state-of-the-art medical and research center. Twenty-one faculty members who are leaders in basic, translational, and clinical research on various aspects of aging are available to mentor trainees. In addition to the in depth scientific training that they will receive from their mentors, postdoctoral fellows (three per year) will participate in workshops for grant writing and career development. Fellows will be expected to submit applications for independent grants and to participate in a full array of programmatic activities, including but not limited to journal clubs, seminars, national scientific meetings, and training in the responsible conduct of research. This training program values individuals from diverse educational and societal backgrounds and will benefit from the unique perspectives they bring to solving complex medical problems and reducing the burden of age-related diseases on patients, their families, and our society.